real-world use: which workflow works best for DALL-E?

I think real-world and best is the key part of this topic. A practical approach is to define the outcome you want, test it with a small example, and then check quality, speed and reliability separately. It is usually easier to troubleshoot when each change is tested on its own.
 
For real-world use: which workflow works best for DALL-E?, I would separate the problem into setup, output quality and repeatability. real-world and best fits into that because it can change the result quite a lot depending on the workflow. The original point — "There are several ways to approach DALL-E, so I wanted to compare experiences. I am particularly interested in real-world use and customisation. I would like to compare approaches…" — gives a useful starting point for that comparison.
 
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A useful way to look at real-world use: which workflow works best for DALL-E? is to focus first on real-world and best. That tends to make the trade-offs easier to compare. If you share the exact setup, it would be easier to narrow down which part matters most.